Cancer Terms

TFIIA Alpha-p55

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Basal Transcription Factor -> TFIIA Alpha-p55

TFIIA Alpha-p55 Definition

Encoded by human GTF2A1 Gene, TFIIA Alpha p55 is a 55-kDa post-translationally processed precursor of the 35-kD alpha (N-terminal) and 19-kD beta (C-terminal) subunits of general transcription initiation factor TFIIA. These subunits and the 12-kDa gamma subunit (GTF2A2 Gene) form a six strand beta-barrel that interacts with TBP and a separate four-helix bundle positioned just upstream of the TBP-TATA complex. Accurate transcription initiation on class II genes involves ordered assembly of RNA polymerase II and general initiation factors. (NCI)

TFIIA Alpha-p55 Synonyms

TFIIA Alpha p55, GTF2A1

Terms in TFIIA Alpha-p55 category



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