TGIF1 wt Allele
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TGIF1 wt Allele Definition
Human TGIF1 wild-type allele is located in the vicinity of 18p11.3 and is approximately 46 kb in length. This allele, which encodes homeobox protein TGIF1, may play a role in regulation of TGF beta signalling (via the inhibition of SMAD2 phosphorylation). Mutations in this gene are associated with holoprosencephaly 4.
TGIF1 wt Allele Synonyms
TGIF1 wt Allele, HPE4, MGC 5066, MGC39747, TGFB-Induced Factor Homeobox 1 wt Allele, TGIF
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