Cancer Terms

THRB wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> Thyroid Hormone Receptor Gene -> THRB Gene -> THRB wt Allele

THRB wt Allele Definition

Human THRB wild-type allele is located in the vicinity of 3p24.2 and is approximately 377 kb in length. This allele, which encodes thyroid hormone receptor beta-1 protein, plays a role in the progression of the thyroid hormone signaling pathway. Mutations in the gene, which occur in the hormone-binding region, are associated with generalized resistance to thyroid hormone.

THRB wt Allele Synonyms

THRB wt Allele, ERBA2, THR1, THRB1, THRB2, Thyroid Hormone Receptor Beta Gene, Thyroid Hormone Receptor, Beta (Erythroblastic Leukemia Viral (V-ERB-A) Oncogene Homolog 2, Avian) wt Allele

Terms in THRB wt Allele category



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