THRB wt Allele
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THRB wt Allele Definition
Human THRB wild-type allele is located in the vicinity of 3p24.2 and is approximately 377 kb in length. This allele, which encodes thyroid hormone receptor beta-1 protein, plays a role in the progression of the thyroid hormone signaling pathway. Mutations in the gene, which occur in the hormone-binding region, are associated with generalized resistance to thyroid hormone.
THRB wt Allele Synonyms
THRB wt Allele, ERBA2, THR1, THRB1, THRB2, Thyroid Hormone Receptor Beta Gene, Thyroid Hormone Receptor, Beta (Erythroblastic Leukemia Viral (V-ERB-A) Oncogene Homolog 2, Avian) wt Allele
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