TIL TRANSDUCED GENE CODING FOR TNF
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Retired Concept 2004 -> TIL TRANSDUCED GENE CODING FOR TNF
TIL TRANSDUCED GENE CODING FOR TNF Definition
Tumor infiltrating lymphocytes (TIL) that are genetically modified in vitro to express the protein cytokine tumor necrosis factor (TNF) with potential antineoplastic activity. After isolation from the patient and genetic modification, TNF gene-transduced TIL are transferred back to the same patient in an attempt to deliver cytotoxic TNF selectively to the tumor microenvironment, thereby potentially avoiding TNF-related systemic toxicity. (NCI04)
TIL TRANSDUCED GENE CODING FOR TNF Synonyms
TNF Gene Transduced TIL
Terms in TIL TRANSDUCED GENE CODING FOR TNF category
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