TIP60
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
Enzyme ->
Transferase ->
Acyltransferase ->
Histone Acetylase -> TIP60
TIP60 Definition
TIP60 interacts with the activation domain of Tat, an activator of HIV gene expression. The yeast SAS2 transcriptional silencing protein, important for exit from the cell cycle, is closely related to TIP60. The widely expressed cell surface amyloid-beta precursor protein is cleaved by gamma-secretase and its cytoplasmic tail forms a multimeric complex with the nuclear adaptor protein FE65 and the histone acetyltransferase TIP60. This complex potently stimulates transcription. (from OMIM 601409 and NCI)
TIP60 Synonyms
TIP60, HIV-1 Tat Interactive Protein, 60kDa, HTATIP, TAT Interacting Protein 60, cPLA2 Interacting Protein
Terms in TIP60 category
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