Cancer Terms

TNFRSF5 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Cytokine Receptor Gene -> TNF Receptor Family Gene -> TNFRSF5 Gene -> TNFRSF5 wt Allele

TNFRSF5 wt Allele Definition

Human CD40 wild-type allele is located within 20q12-q13.2 and is approximately 186 kb in length. This allele, which encodes tumor necrosis factor receptor superfamily member 5 protein, is involved in the modulation of T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. Deletions in the gene are associated with hyper-IgM immunodeficiency type 3. The gene may play a role in the pathogenesis of Alzheimer's disease.

TNFRSF5 wt Allele Synonyms

CD40 wt Allele, Bp50, CD40 Antigen (TNF Receptor Superfamily Member 5) wt Allele, CDW40, MGC9013, TNFRSF5, TNFRSF5 Gene, Tumor Necrosis Factor Receptor Superfamily Member 5 Gene, p50

Terms in TNFRSF5 wt Allele category



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