TOP3B wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Isomerase Gene -> TOP3B Gene -> TOP3B wt Allele

TOP3B wt Allele Definition

Human TOP3B wild-type allele is located in the vicinity of 22q11.22 and is approximately 26 kb in length. This allele, which encodes DNA topoisomerase 3-beta-1 protein, is involved in the ATP-independent breakage of negatively supercoiled single-stranded DNA and subsequent passage/rejoining of the broken DNA.

TOP3B wt Allele Synonyms

TOP3B wt Allele, Topoisomerase (DNA) II Beta 180kDa wt Allele

Terms in TOP3B wt Allele category

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