TP53 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> TP53 Gene -> TP53 wt Allele

TP53 wt Allele Definition

Human TP53 wild-type allele is located in the vicinity of 17p13.1 and is approximately 19 kb in length. This allele, which encodes cellular tumor antigen p53 protein, plays a role in cell cycle regulation during the G0/G1transition. Alterations of the TP53 gene occur as both somatic and germline mutations in human malignancies in select cancer-prone families with Li-Fraumeni syndrome.

TP53 wt Allele Synonyms

TP53 wt Allele, P53, TP53, TRP53, Tumor Protein P53 (Li-Fraumeni Syndrome) wt Allele, Tumor Protein p53 Gene, p53, p53 gene

Terms in TP53 wt Allele category

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