TPO wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Oxidoreductase Gene -> TPO Gene -> TPO wt Allele

TPO wt Allele Definition

Human TPO wild-type allele is located within 2p25 and is approximately 129 kb in length. This allele, which encodes thyroid peroxidase protein, plays a role in biosynthesis of thyroxine and triiodothyronine. Heritable polymorphisms in the TPO gene commonly result in total iodine organification defect which, in turn, causes severe congenital hypothyroidism.

TPO wt Allele Synonyms

TPO wt Allele, MSA, TPX, Thyroid Peroxidase wt Allele

Terms in TPO wt Allele category

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