Cancer Terms

Tadalafil

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Phosphodiesterase Inhibitor -> cGMP Phosphodiesterase Inhibitor -> Tadalafil

Tadalafil Definition

A carboline-based compound with vasodilatory activity. Tadalfil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalfil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

Tadalafil Synonyms

Tadalafil, (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, Cialis, Ic351, TADALAFIL

Terms in Tadalafil category



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