Cancer Terms

Tecogalan Sodium

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Angiogenesis Inhibitor -> Angiogenesis Activator Inhibitor -> Tecogalan Sodium

Tecogalan Sodium Definition

A sulfated polysaccharide isolated from various Arthrobacter bacterial species. Possessing potential antiangiogenic and antineoplastic properties, tecogalan binds to basic fibroblast growth factor (bFGF), thereby preventing bFGF from binding to its receptors. Disruption of this receptor binding results in the inhibition of bFGF-stimulated endothelial cell growth, proliferation, and migration. (NCI04)

Tecogalan Sodium Synonyms

Tecogalan Sodium, DS-4152, SP-PG, Sulfated Polysaccharide Tecogalan DS-4152

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