Telomeric Repeat Binding Factor-1

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> DNA Binding Protein -> Telomeric-Repeat Binding Factor -> Telomeric Repeat Binding Factor-1

Telomeric Repeat Binding Factor-1 Definition

This protein is a telomere specific binding protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. (from LocusLink)

Telomeric Repeat Binding Factor-1 Synonyms

Telomeric Repeat Binding Factor 1, TERF1, Telomeric Repeat Binding Factor (NIMA-Interacting) 1, Telomeric-Repeat Binding Factor 1

Terms in Telomeric Repeat Binding Factor-1 category

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