Cancer Terms

Telomeric Repeat Binding Factor-2

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> DNA Binding Protein -> Telomeric-Repeat Binding Factor -> Telomeric Repeat Binding Factor-2

Telomeric Repeat Binding Factor-2 Definition

This protein is a telomere specific binding protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. (LocusLink)

Telomeric Repeat Binding Factor-2 Synonyms

Telomeric Repeat Binding Factor 2, TERF2, Telomeric-Repeat Binding Factor 2

Terms in Telomeric Repeat Binding Factor-2 category



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