Cancer Terms

Tetradecanoylphorbol Acetate

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inhibitor -> Tetradecanoylphorbol Acetate

Tetradecanoylphorbol Acetate Definition

A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity. (NCI04)

Tetradecanoylphorbol Acetate Synonyms

Tetradecanoylphorbol Acetate, 12-O-tetradecanoylphorbol-13-acetate, Lonomycin, PMA, PMAS, Phorbol Myristate Acetate, TPA

Terms in Tetradecanoylphorbol Acetate category



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