Therapeutic 70-kD Heat-Shock Protein
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Biological Agent ->
Antigen ->
Vaccine Antigen -> Therapeutic 70-kD Heat-Shock Protein
Therapeutic 70-kD Heat-Shock Protein Definition
A recombinant peptide that is chemically identical to or similar to the endogenous 70-kD heat shock protein (HSP70). HSP70 is a molecular chaperone that prevents physiologic stress-induced cell death by inhibiting both caspase-dependent and caspase-independent apoptosis. Because this peptide is often overexpressed in tumor cells, autologous vaccination with HSP70 derived from tumor cells may stimulate the host immune system to mount a tumoricidal cytotoxic T lymphocyte (CTL) response. (NCI04)
Therapeutic 70-kD Heat-Shock Protein Synonyms
Recombinant 70-kD Heat-Shock Protein, 70-kD Heat-Shock Protein, HSP70, Heat Shock Protein 70
Terms in Therapeutic 70-kD Heat-Shock Protein category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.