Cancer Terms

Therapeutic Dehydroepiandrosterone

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Therapeutic Hormone -> Therapeutic Steroid Hormone -> Therapeutic Androgen -> Therapeutic Dehydroepiandrosterone

Therapeutic Dehydroepiandrosterone Definition

A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and antiglucocorticoid activities. (NCI04)

Therapeutic Dehydroepiandrosterone Synonyms

Prasterone, 17-Hormoforin, 3beta-Hydroxyandrost-5-en-17-one, 5,6-Dehydroisoandrosterone, DHEA, Dehydroepiandrosterone, Dehydroisoandrosterone, Diandron, Fidelin, GL701, PRASTERONE, Therapeutic Dehydroepiandrosterone, dehydroepiandrosterone

Terms in Therapeutic Dehydroepiandrosterone category



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