Therapeutic Insulin-Like Growth Factor

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Agent -> Therapeutic Growth Factor -> Therapeutic Insulin-Like Growth Factor

Therapeutic Insulin-Like Growth Factor Definition

A recombinant human antiapoptotic growth factor. Recombinant insulin-like growth factor (IGF) binds to and activates the insulin and IGF receptors; activation of these receptors initiates intracellular phosphorylation events and the activation of several signaling pathways, thereby promoting cellular proliferation and inhibiting apoptosis. High levels of circulating endogenous insulin-like growth factor may indicate a poor prognosis in some cancers. (NCI04)

Therapeutic Insulin-Like Growth Factor Synonyms

Recombinant Insulin-Like Growth Factor, Rh IGF, Rh Insulin Like Growth Factor, Somatomedin

Terms in Therapeutic Insulin-Like Growth Factor category

Recombinant IGF-I
Recombinant IGF-II