Cancer Terms

Tinidazole

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Anti-Infective Agent -> Antiparasitic Agent -> Antiprotozoal Agent -> Tinidazole

Tinidazole Definition

A 5-nitroimidazole derivative with antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitrite anions and metronidazole. Metronidazole's nitro group in turn is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and DNA strand breaks with multiple hits having an additive effect and ultimately leading to cell death.

Tinidazole Synonyms

Tinidazole, Fasigyn, Simplotan, TDZ, TINIDAZOLE, Tindamax, tinidazole

Terms in Tinidazole category



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