Tiopronin
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Tiopronin Definition
An acylated sulfhydryl-containing derivative of glycine with reducing and complexing properties. Tiopronin breaks the disulphide bond of cystine and binds the sulfhydryl group of the resultant cysteine monomers to form a soluble tiopronin-cysteine-mixed disulfide, which is more water-soluble than cystine and is readily excreted. This leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation.
Tiopronin Synonyms
Tiopronin, (2-Mercaptopropionyl)glycine, Glycine, N-(2-mercapto-1-oxopropyl)-, TIOPRONIN, Thiola, Thiolpropionamidoacetic Acid
Terms in Tiopronin category
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