Tirofiban Hydrochloride
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Tirofiban Hydrochloride Definition
The hydrochloride salt form of tirofiban, a non-peptide tyrosine derivative with anticoagulant property. Tirofiban antagonizes fibrinogen binding to the platelet cell surface receptor, glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. The antagonism prevents adenylyl cyclase activation, which mediated via GP IIb/IIIa receptor complex, and results in decreased levels of cAMP and thereby interferes with platelet membrane function and subsequent platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time.
Tirofiban Hydrochloride Synonyms
Tirofiban Hydrochloride, Aggrastat, MK 383, N-(Butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-L-tyrosine Monohydrochloride, TIROFIBAN HYDROCHLORIDE, Tirofiban Hydrochloride Monohydrate
Terms in Tirofiban Hydrochloride category
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