Cancer Terms

Tolterodine Base

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Nervous System -> Anticholinergic Agent -> Antimuscarinic Agent -> Tolterodine Base

Tolterodine Base Definition

A benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects.

Tolterodine Base Synonyms

Tolterodine, TOLTERODINE

Terms in Tolterodine Base category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.