Transcription Coregulator Gene

Cancer Terms -> Gene -> Regulatory Gene -> Transcription Coregulator Gene

Transcription Coregulator Gene Definition

RNA polymerase II transcription of Class II genes involves the TFIID transcription complex comprised of general factors, including TBP, TFIIA, TFIIB, TFIIE, TFIIF, TFIIG/J, and TFIIH, as well as gene-specific factors that include TAFs, which interact with regulatory protein activation domains to enhance transcription. A second group of cofactors includes PC1, PC2, and PC3, which have a strong positive influence on transcription. A third group of factors suppress transcription. The combined action of general and gene-specific regulators encoded by transcription coactivator genes determines appropriate gene expression. (NCI)

Transcription Coregulator Gene Synonyms

Transcription Coregulator Gene, Transcription Coactivator/Corepressor Gene, Transcriptional Coregulator Gene

Terms in Transcription Coregulator Gene category

CTCF Gene
ID2 Gene
PRDM4 Gene
RCAN1 Gene
Transcription Coactivator Gene
Transcription Corepressor Gene