Transcription Initiation Factor-IIA Gamma Chain

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Basal Transcription Factor -> Transcription Initiation Factor-IIA Gamma Chain

Transcription Initiation Factor-IIA Gamma Chain Definition

Encoded by human GTF2A2 Gene, Transcription Initiation Factor IIA Gamma Chain is the 12-kD gamma subunit of TFIIA, along with 35-kD alpha and 19-kD beta subunits. Accurate transcription initiation on class II genes involves ordered assembly of RNA polymerase II and general initiation factors. The first step involves TATA box recognition by TBP, which may be regulated by TFIIA, a factor that interacts with both TBP and a TAF in TFIID. The TFIIA subunits form a six strand beta-barrel that interacts with TBP and a separate four-helix bundle positioned just upstream of the TBP-TATA complex. (NCI)

Transcription Initiation Factor-IIA Gamma Chain Synonyms

Transcription Initiation Factor IIA Gamma Chain, GTF2A2, General Transcription Factor IIA2 12kDa, TFIIA p12 Subunit, TFIIA-12, TFIIA-Gamma, TFIIAS

Terms in Transcription Initiation Factor-IIA Gamma Chain category

---

Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.