Cancer Terms

Transcription Initiation Factor-IIF Beta Subunit

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Basal Transcription Factor -> Transcription Initiation Factor-IIF Beta Subunit

Transcription Initiation Factor-IIF Beta Subunit Definition

Encoded by human GTF2F2 Gene, 30-kD Transcription Initiation Factor IIF Beta Subunit is the small subunit of transcription factor TFIIF. By distinct functional domains, TFIIF affects RNA polymerase II during initiation and elongation. It assists TFIIB in recruiting RNA polymerase II into a preinitiation complex and suppresses transient polymerase pausing. TFIIF beta initiation activity is mediated by a DNA-binding C-terminal domain. Elongation is mediated by sequences upstream of the C-terminus, where RNA polymerase II may bind, as well as by sequences near the N-terminus. (NCI)

Transcription Initiation Factor-IIF Beta Subunit Synonyms

Transcription Initiation Factor IIF Beta Subunit, GTF2F2, General Transcription Factor IIF2 30kDa, TFIIF-Beta, Transcription Initiation Factor RAP30

Terms in Transcription Initiation Factor-IIF Beta Subunit category



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