Transcription Initiation Factor-IIF Beta Subunit
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Transcription Initiation Factor-IIF Beta Subunit Definition
Encoded by human GTF2F2 Gene, 30-kD Transcription Initiation Factor IIF Beta Subunit is the small subunit of transcription factor TFIIF. By distinct functional domains, TFIIF affects RNA polymerase II during initiation and elongation. It assists TFIIB in recruiting RNA polymerase II into a preinitiation complex and suppresses transient polymerase pausing. TFIIF beta initiation activity is mediated by a DNA-binding C-terminal domain. Elongation is mediated by sequences upstream of the C-terminus, where RNA polymerase II may bind, as well as by sequences near the N-terminus. (NCI)
Transcription Initiation Factor-IIF Beta Subunit Synonyms
Transcription Initiation Factor IIF Beta Subunit, GTF2F2, General Transcription Factor IIF2 30kDa, TFIIF-Beta, Transcription Initiation Factor RAP30
Terms in Transcription Initiation Factor-IIF Beta Subunit category
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