Cancer Terms

Transcriptional Co-Activator-CRSP100

Cancer Terms -> Gene Product -> Protein -> Protein Complex Subunit -> Transcriptional Co-Activator-CRSP100

Transcriptional Co-Activator-CRSP100 Definition

Encoded by human CRSP4 Gene, Cofactor Required for Sp1 Transcriptional Activation Subunit 4 is 100-kD protein of the CRSP (Cofactor Required for SP1 activation) complex, which, along with TFIID, is required for efficient activation of gene transcription by SP1, a transcription factor that recognizes enhancer sites in target DNA. Many CRSP complex proteins are also components of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins that interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. (NCI)

Transcriptional Co-Activator-CRSP100 Synonyms

Cofactor Required for Sp1 Transcriptional Activation Subunit 4, CRSP100, CRSP4

Terms in Transcriptional Co-Activator-CRSP100 category



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