Transforming Growth Factor Beta Receptor II

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Receptor -> Cell Surface Receptor -> Receptor Serine-Threonine Kinase -> Transforming Growth Factor Beta Receptor II

Transforming Growth Factor Beta Receptor II Definition

The cell surface binding proteins for tumor-derived growth factor- beta. There are three receptors, Type I and Type II together form a heterodimeric signaling complex that is essential for the transduction of the anti-proliferative signals of TGF-beta. Type III is a transmembrane proteoglycan with a large extracellular domain and a cytoplasmic domain that lacks an obvious signaling motif.

Transforming Growth Factor Beta Receptor II Synonyms

Transforming Growth Factor Beta Receptor II, TGF B Receptor, TGF-Beta Type II Receptor, TGFBR2, Transforming Growth Factor Beta Receptor

Terms in Transforming Growth Factor Beta Receptor II category

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