Transforming Growth Factor-Beta

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Growth Factor -> Transforming Growth Factor -> Transforming Growth Factor-Beta

Transforming Growth Factor-Beta Definition

Factor synthesized in a wide variety of tissues including platelets, placenta, and both normal and transformed cell lines. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta also has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. There are at least three forms of TGF-beta: TGF-beta1, TGF-beta2, and TGF-beta1.2. The latter is a heterodimer made up of both TGF-beta1 and TGF-beta2.

Transforming Growth Factor-Beta Synonyms

Transforming Growth Factor-Beta, Bone-Derived Transforming Growth Factor, Milk Growth Factor, TGF B, TGF-Beta

Terms in Transforming Growth Factor-Beta category

Bone Morphogenetic Protein
Endometrial Bleeding Associated Factor
Glial Cell Line Derived Neurotrophic Factor
Growth Differentiation Factor-9
Left-Right Determination Factor-B
Neurturin
Placental TGF-Beta