Translation Initiation Factor-EIF-2B Alpha Subunit
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Translation Initiation Factor-EIF-2B Alpha Subunit Definition
Encoded by human EIF2B1 Gene (EIF2B Alpha/Beta/Delta Family), 305-aa 34-kDa Translation Initiation Factor EIF-2B Alpha Subunit acts in EIF2B, a heteropentameric complex of alpha, beta, gamma, delta, and epsilon subunits essential for protein synthesis that catalyzes GDP/GTP exchange of its Eukaryotic Initiation Factor 2 substrate. For EIF2 to perform additional rounds of initiation, it must be recycled by GDP/GTP exchange. Rat Eif2b1 protein is 92% identical to human EIF2B1. EIF2B1 defects cause VWM. (NCI)
Translation Initiation Factor-EIF-2B Alpha Subunit Synonyms
Translation Initiation Factor EIF-2B Alpha Subunit, EIF-2-Beta, EIF-2B, EIF-2B Alpha, EIF-2B GDP-GTP Exchange Factor, EIF2B, EIF2B1, EIF2BA, Eukaryotic Translation Initiation Factor 2B, Eukaryotic Translation Initiation Factor 2B Subunit 1 Alpha 26-kDa
Terms in Translation Initiation Factor-EIF-2B Alpha Subunit category
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