Cancer Terms

Triethylenemelamine

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Alkylating Agent -> Antineoplastic Alkylating Agent -> Ethylenimine Compound -> Triethylenemelamine

Triethylenemelamine Definition

A trisaziridine alkylating agent with antineoplastic and carcinogenic properties. Used to induce cancer in experimental animal models, triethylenemelamine ethylates DNA, resulting in inhibition of DNA replication, unscheduled DNA synthesis, chromosomal aberrations, and sister chromatid exchanges. This agent also exhibits reproductive toxicities. (NCI04)

Triethylenemelamine Synonyms

Triethylenemelamine, TEM, Triethylene Melamine

Terms in Triethylenemelamine category



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