Trimethoprim-Sulfamethoxazole

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Anti-Infective Agent -> Combination Anti-Infective Agent -> Trimethoprim-Sulfamethoxazole

Trimethoprim-Sulfamethoxazole Definition

A synthetic combination of two antibacterial agents, trimethoprim and sulfamethoxazole. This synergistic combination, also known as Co-Trimoxazole, inhibits two sequential steps in the bacterial metabolism of folic acid. Trimethoprim is a pyrimidine inhibitor of dihydrofolate reductase; sulfamethoxazole is a sulfamide inhibitor of bacterial dihydrofolate synthase. (NCI04)

Trimethoprim-Sulfamethoxazole Synonyms

Trimethoprim-Sulfamethoxazole, Bactrim, Bactrim DS, Bactrimel, Centran, Centrin, Co-Trimoxazole, Cotrim, Cotrimoxazole, Eslectin, Insozalin, SMZ-TMP, Septra, Sulfamethoprim, Sulfatrim, Sulmeprim, TMP-SMX, Trimedin, Trimezole, Uroplus, co-trimoxazole, trimethoprim-sulfamethoxazole

Terms in Trimethoprim-Sulfamethoxazole category

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