Cancer Terms

Trioxifene Mesylate

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Chemopreventive Agent -> Selective Estrogen Receptor Modulator -> Trioxifene Mesylate

Trioxifene Mesylate Definition

A mesylate salt form of trioxifene, a nonsteroidal selective estrogen receptor modulator (SERM). Trioxifene competitively inhibits the binding of estradiol to estrogen receptor alpha (ER alpha), resulting in ER alpha-mediated gene expression. Clinical development of Trioxifene has not proceeded because of lack of superior results over tamoxifen and side effect profile. (NCI)

Trioxifene Mesylate Synonyms

Trioxifene Mesylate, Ly-133314

Terms in Trioxifene Mesylate category



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