Tyrosinase-Related Protein-1
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Tyrosinase-Related Protein-1 Definition
A glycoprotein catalase with a membrane-spanning domain and conserved positions of cysteine and histidine residues, TRP1 shares 40% amino acid sequence homology with mouse tyrosinase but has no tyrosinase activity and converts 5, 6-dihydroxyindole-2-carboxylic acid to melanochrome in premelanosomes. TRP1 is identical to melanosomal protein, gp75. (from OMIM 115501 and NCI)
Tyrosinase-Related Protein-1 Synonyms
Tyrosinase-Related Protein 1, B-Protein, Catalase B, Glycoprotein 75, TRP-1, TYRP, TYRP1, Tyrosinase Related Protein-1
Terms in Tyrosinase-Related Protein-1 category
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