Tyrosyl-tRNA Synthetase
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Tyrosyl-tRNA Synthetase Definition
Encoded by human YARS Gene, the 528-amino acid Tyrosyl-tRNA Synthetase polypeptide belongs to the Class-I Aminoacyl-tRNA Synthetase Family. Likely to be among the first proteins to appear in evolution, amino acyl-tRNA synthetases catalyze tRNA amino acylation by their cognate amino acid. Under apoptotic conditions, tyrosyl-tRNA synthetase may be secreted and cleaved into an N-terminal IL8-like cytokine fragment that harbors the catalytic site and a C-terminal EMAP II-like cytokine fragment. (OMIM, Swiss-Prot, LocusLink, and NCI)
Tyrosyl-tRNA Synthetase Synonyms
Tyrosyl-tRNA Synthetase, EC 6.1.1.1, Tyrosine-transfer RNA Ligase, Tyrosyl-tRNA Ligase, YARS
Terms in Tyrosyl-tRNA Synthetase category
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