Tyrphostin B42
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Tyrphostin B42 Definition
A member of the tyrphostin family of tyrosine kinase inhibitors that inhibits epidermal growth factor receptor, blocks leukemic cell growth in vitro and in vivo by inducing programmed cell death. Inhibits the constitutive activation of STAT-3 DNA binding and IL-2-induced growth of Mycosis fungoides tumor cells. (NCI)
Tyrphostin B42 Synonyms
Tyrphostin B42, 2-Cyano-3-(3,4-Dihydroxyphenyl)-N-(Phenylmethyl)-2-Propenamide, AG 490
Terms in Tyrphostin B42 category
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