UBA Domain
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UBA Domain Definition
The UBA-domain is a sequence motif found in multiple enzyme classes having connections to ubiquitin and the ubiquitination pathway, including human ubiquitin isopeptidase T and several other ubiquitin C-terminal hydrolases catalyzing regulatory protein-deubiquitination. Mammalian proto-oncogene c-cbl is a protein interacting with multiple signal transduction factors. Cbl has recently been shown to undergo regulatory ubiquination upon macrophage stimulation.
UBA Domain Synonyms
UBA Domain, Ubiquitin-Associated Domain
Terms in UBA Domain category
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