UGT1A1 28 Polymorphism
Cancer Terms ->
Gene ->
Enzyme Gene ->
Transferase Gene ->
Glycosyltransferase Gene ->
UGT1A1 Gene -> UGT1A1 28 Polymorphism
UGT1A1 28 Polymorphism Definition
Human UGT1A1*28 allele is located in the vicinity of 2q37 and is approximately 13 kb in length. This allele, which encodes UDP-glucuronosyltransferase 1-1 protein, plays a role in the transformation of small lipophilic molecules into water-soluble metabolites. UGT1A1*28 allele has a polymorphism in the promoter region that is associated with decreased transferase activity and decreases in both tolerance and effectiveness of cancer therapeutics and antiviral drugs.
UGT1A1 28 Polymorphism Synonyms
UGT1A1*28 Allele, UDP Glycosyltransferase 1 Family, Polypeptide A1*28 Allele, UGT1A1 (TA)7 Allele
Terms in UGT1A1 28 Polymorphism category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.