Cancer Terms

Ubiquitin Protein Ligase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Ligase -> Ubiquitin Protein Ligase

Ubiquitin Protein Ligase Definition

Ubiquitin protein ligase enzymes catalyze the formation of a covalent peptide bond between the carboxy-terminal glycine of ubiquitin proteins and lysine alpha-amino group of other proteins. This typically marks proteins for either nonlysosomal proteasomal degradation or targeted transport. Ubiquitination requires sequential action of an activating enzyme, a conjugating enzyme, and a ligase.

Ubiquitin Protein Ligase Synonyms

Ubiquitin Protein Ligase, Ubiquitin Protein Ligase Complex

Terms in Ubiquitin Protein Ligase category



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