Cancer Terms

Ubiquitin Specific Protease-8

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Hydrolase -> Protease -> Ubiquitin Specific Protease-8

Ubiquitin Specific Protease-8 Definition

Encoded by human USP8 Gene (C19 Peptidase Family), Ubiquitin Specific Protease 8 is a deubiquitinating enzyme related to the TRE2 oncogene product that cleaves at the carboxyl terminus of ubiquitin. In chronic myeloproliferative disorder, an oncogenic fusion of p85-beta occurs with the carboxyl end of USP8. (OMIM, Swiss-Prot, LocusLink, and NCI)

Ubiquitin Specific Protease-8 Synonyms

Ubiquitin Specific Protease 8, Deubiquitinating Enzyme 8, Deubiquitinating Enzyme HUMORF8, USP8, Ubiquitin Carboxyl-Terminal Hydrolase 8, Ubiquitin Thiolesterase 8, Ubiquitin-Specific Processing Protease 8

Terms in Ubiquitin Specific Protease-8 category



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