Ubiquitin-Conjugating Enzyme-E2D2
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Ubiquitin-Conjugating Enzyme-E2D2 Definition
Encoded by human UBE2D2 Gene (E2 Ubiquitin-Conjugating Enzyme Family), 147-aa 16.7-kDa Ubiquitin-Conjugating Enzyme E2D 2 targets selective degradation of short-lived and abnormal proteins, such as E6/E6-AP-induced p53 ubiquitination, through covalent attachment of ubiquitin, the second step of ubiquitin conjugation. UBE2D2 interacts with the SCF/E3 ubiquitin ligase complex. Ubiquitination involves E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. (NCI)
Ubiquitin-Conjugating Enzyme-E2D2 Synonyms
Ubiquitin-Conjugating Enzyme E2D 2, E2(17)KB 2, UBC4/5, UBE2D2, Ubiquitin Carrier Protein, Ubiquitin-Conjugating Enzyme E2-17 kDa 2, Ubiquitin-Protein Ligase
Terms in Ubiquitin-Conjugating Enzyme-E2D2 category
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