Cancer Terms

Vatalanib Succinate

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Tyrosine Kinase Inhibitor -> Vatalanib Succinate

Vatalanib Succinate Definition

The succinate salt of vatalanib, an anilinophthalazine derivative, with antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.

Vatalanib Succinate Synonyms

Vatalanib Succinate, 1-[4-Chloroanilino]-4-[4-pyridylmethyl]phthalazine Succinate, Butanedioic Acid, Compd. with N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine (1:1), CGP 79787D, PTK 787, PTK-787, PTK787, PTK787/ZK 222584, VATALANIB SUCCINATE, ZK 222584

Terms in Vatalanib Succinate category



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