Verapamil Hydrochloride
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Verapamil Hydrochloride Definition
The hydrochloride form of Verapamil, which is a phenylalkylamine calcium channel blocking agent. Verapamil inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)
Verapamil Hydrochloride Synonyms
Verapamil Hydrochloride, (+-)-Verapamil hydrochloride, Calan, Isoptin SR, VERAPAMIL HYDROCHLORIDE, Verapamil hydrochloride, Verelan
Terms in Verapamil Hydrochloride category
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