WT1 Protein
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WT1 Protein Definition
A potential regulator of transcription, WT1 belongs to the EGR family of C2H2 zinc-finger proteins and binds to the DNA sequence 5'-CGCCCCCGC-3'. Inactivation of WT1 is one cause of Wilm's Tumor, an embryonal malignancy of the kidney. Defects in WT1 are also associated with Denys-Drash Syndrome (DDS) and Diffuse Mesangial Sclerosis (DMS). (from SWISS-PROT P19544, OMIM 194070, and NCI)
WT1 Protein Synonyms
WT1 Protein, WT1, WT1 Gene Product, WT33
Terms in WT1 Protein category
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