Yolk Sac Tumor

Cancer Terms -> Diseases Disorders and Findings -> Diseases and Disorders -> Neoplasm -> Neoplasm by Morphology -> Germ Cell Neoplasm -> Malignant Germ Cell Neoplasm -> Yolk Sac Tumor

Yolk Sac Tumor Definition

A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum.

Yolk Sac Tumor Synonyms

Yolk Sac Tumor, Endodermal Sinus Neoplasm, Endodermal Sinus Tumor, Yolk Sac Neoplasm, Yolk Sac Tumour Site Unspecified

Terms in Yolk Sac Tumor category

Adult Yolk Sac Tumor