Cancer Terms

Zanamivir

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Anti-Infective Agent -> Antiviral Agent -> Miscellaneous Antiviral Agent -> Zanamivir

Zanamivir Definition

A sialic acid analog and a neuraminidase inhibitor with antiviral property. Zanamivir selectively inhibits influenza A and B virus neuraminidase, a viral surface glycoprotein, which mediates the cleavages of sialic acid residues on the surfaces of host cells and influenza viral envelopes. The uncleaved sialic acid residues were bound by viral hemagglutinin, thereby resulting in viral aggregation at the host cell surface, thereby preventing the release of influenza virus particles into the respiratory tract.

Zanamivir Synonyms

Zanamivir, 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic Acid, 5-Acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic Acid, GANA, GG 167, Relenza, ZANAMIVIR

Terms in Zanamivir category



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