Ziconotide
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Pharmacologic Substance ->
Agent Affecting Nervous System ->
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Nonnarcotic Analgesic -> Ziconotide
Ziconotide Definition
A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with analgesic activity. Ziconotide appears to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission from pain-sensing primary nociceptors. This agent may exhibit significant analgesic activity in refractory pain.
Ziconotide Synonyms
Ziconotide, Prialt, SNX 111, SNX-111, ZICONOTIDE, ziconotide
Terms in Ziconotide category
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