hBRM
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
Regulatory Protein ->
Transcription Regulatory Protein ->
SWI2-SNF2 Family Protein -> hBRM
hBRM Definition
An ATPase subunit of the SWI/SNF enzyme, BRM belongs to the SNF2/RAD54 helicase family, contains a bromodomain, and is a co-activator for nuclear hormone receptors. BRM is a yeast transcription factor SWI2 homologue. Nuclear BRM is phosphorylated, excluded from condensed chromosomes, and strongly reduced during mitosis; phosphorylation does not disrupt the association with SNF5, but correlates with decreased affinity for the nuclear structure in early M-phase. SWI/SNF enzymes promote MyoD-mediated muscle differentiation by altering chromatin structure in promoter regions of differentiation-specific loci. (from SWISS-PROT P51531, OMIM 600014, and NCI)
hBRM Synonyms
hBRM, BRM Homolog, BRM/SNF2alpha, Human Brahma, Possible Global Transcription Activator SNF2L2, SNF2-Like 2, SNF2/SWI2 Homolog, SNF2L2, SNF2LA, SNF2alpha, SWI/SNF-Related, Matrix-Associated, Actin-Dependent Regulator of Chromatin, Subfamily A, Member 2, Smarca2, Sucrose Nonfermenting Homolog-Like 2
Terms in hBRM category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.